Resumen del episodio
886. Put "GLP-1" on a label and you can sell almost anything right now: supplements, snacks, drink powders, even a gadget that sits next to your toilet. Some of these products are designed for people taking GLP-1 medications, who can have real nutritional needs. Others promise to boost your body's own GLP-1 as a path to weight loss. That second pitch is a lot shakier, and the reason comes down to what these medications are and how they work. Monica separates the science from the marketing: What GLP-1 is, and what this gut hormone does after you eat Why semaglutide, tirzepatide, and retatrutide aren't technically "GLP-1s," and what receptor agonists, dual agonists, and triple agonists are The more accurate names the medical community has proposed for this drug class, and why none of them has stuck How fermentable soluble fiber feeds your gut microbiome, produces short-chain fatty acids, and raises natural GLP-1 Why nobody was talking about boosting natural GLP-1 until these medications took off A bathroom…
886. Put "GLP-1" on a label and you can sell almost anything right now: supplements, snacks, drink powders, even a gadget that sits next to your toilet. Some of these products are designed for people taking GLP-1 medications, who can have real nutritional needs. Others promise to boost your body's own GLP-1 as a path to weight loss. That second pitch is a lot shakier, and the reason comes down to what these medications are and how they work. Monica separates the science from the marketing: What GLP-1 is, and what this gut hormone does after you eat Why semaglutide, tirzepatide, and retatrutide aren't technically "GLP-1s," and what receptor agonists, dual agonists, and triple agonists are The more accurate names the medical community has proposed for this drug class, and why none of them has stuck How fermentable soluble fiber feeds your gut microbiome, produces short-chain fatty acids, and raises natural GLP-1 Why nobody was talking about boosting natural GLP-1 until these medications took off A bathroom…
Episodios
The truth about natural GLP-1 boosters
Escuchado886. Put "GLP-1" on a label and you can sell almost anything right now: supplements, snacks, drink powders, even a gadget that sits next to your toilet. Some of these products are designed for people taking GLP-1 medications, who can have real nutritional needs. Others promise to boost your body's own GLP-1 as a path to weight loss. That second pitch is a lot shakier, and the reason comes down to what these medications are and how they work. Monica separates the science from the marketing: What GLP-1 is, and what this gut hormone does after you eat Why semaglutide, tirzepatide, and retatrutide aren't technically "GLP-1s," and what receptor agonists, dual agonists, and triple agonists are The more accurate names the medical community has proposed for this drug class, and why none of them has stuck How fermentable soluble fiber feeds your gut microbiome, produces short-chain fatty acids, and raises natural GLP-1 Why nobody was talking about boosting natural GLP-1 until these medications took off A bathroom…
What is choline? The nutrient you've probably never heard of
Escuchado885. You need choline every day. Nobody can tell you exactly how much. There's no RDA for choline, because there isn't enough data to set one. What we have instead is an estimate — and it traces back largely to a single study that enrolled only men. The numbers for women were scaled down from there, mostly by body size. Choline is an essential nutrient a lot of people have never heard of. Your liver makes some of it, but not enough, so the rest has to come from food. It's needed to build phosphatidylcholine and the neurotransmitter acetylcholine, and it plays an outsized role in brain development before birth and in early childhood. Monica walks through what's known and what isn't: Why choline gets grouped with the B vitamins even though it isn't one What severe deficiency does to the liver, and what recent research links low intake to in older adults Why there's no RDA for choline, and what an Adequate Intake is actually based on How estrogen changes the picture, and why premenopausal women may need less…
Do we need a prescription to eat better? Talking Food is Medicine with Dariush Mozaffarian
Escuchado884. Your doctor can write you a prescription for a statin or a blood pressure medication. What if they could also prescribe fresh vegetables, and your health insurance paid for them? That’s one of the central ideas behind the Food Is Medicine movement, and cardiologist Dr. Dariush Mozaffarian is one of its leading voices. In his new book, “Food Is Medicine: Healing Our Bodies, Nourishing Our Minds, and Transforming Our Food System,” he argues that diet is the leading driver of chronic disease in the US and that it can also be part of the treatment. Monica Reinagel, MS, LDN, talks with Dr. Mozaffarian about: What “food is medicine” means, and what it doesn’t How produce prescriptions and medically tailored meals and groceries work, and how they differ from SNAP Promising results from pilot programs serving people with type 2 diabetes, high blood pressure, heart failure, and high-risk pregnancies Why opening grocery stores in food deserts didn’t change how people ate What car safety and anti-smoking efforts…
What to eat while breastfeeding and what to skip
Escuchado883. You've probably been told to skip broccoli, garlic, spicy food, sushi, peanuts and even your morning coffee while breast-feeding. How much of that advice holds up? Monica Reinagel, MS, LDN, sorts fact from folklore on what to eat and what to avoid while nursing. She covers the colic theory about cruciferous vegetables, the open question of whether eating peanuts during breast-feeding affects a baby's allergy risk, and the NIH ESCAPE trial now testing it. In this episode, Monica explains Whether cabbage, broccoli and garlic really cause gas and colic in breast-fed babies Why spicy food doesn't harm breast milk, and how your diet shapes your baby's food preferences What the research says about peanuts during breast-feeding, and why early peanut introduction cuts allergy risk How much caffeine and alcohol are considered safe, and how long to wait before nursing Why the pregnancy rules on sushi and soft cheese don't apply while nursing Which fish to choose, how many extra calories and fluids you need, and…
Fasting-mimicking diets: Medical therapy or anti-aging hack?
Escuchado882. Someone in your office comes back from vacation with a box of soups and shakes and announces they're doing a five-day fast. Except they're eating. Fasting-mimicking diets are unusual among viral wellness protocols in that there is a real body of peer-reviewed research behind them. There is also a company selling the five-day kits, founded by the researcher who developed the protocol and funding many of the trials. Both of those things are true at the same time. In this episode, Monica breaks down what the research actually shows: What the five-day protocol involves, including the calorie targets and why it's deliberately low in protein What "fasting mimicking" means, and which effects of a multi-day fast it's trying to reproduce The 2017 trial in 100 healthy adults, where participants lost about five and a half pounds over three months but saw no change in blood sugar, cholesterol, blood pressure, or inflammation Why the subgroup findings are interesting and why they aren't proof The 12-month trial in…